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Cryptococcus neoformans and gattii promote DNA damage in human peripheral blood mononuclear cells
(2018-01-01)
Cryptococcosis, a systemic mycosis capable of disseminating to the central nervous system with frequent lethal effects, is caused by the species Cryptococus neoformans and Cryptococcus gattii. Several infectious agents ...
Increased DNA damage is related to maternal blood glucose levels in the offspring of women with diabetes and mild gestational hyperglycemia
(2015-09-02)
This study aimed at correlating maternal blood glucose levels with DNA damage levels in the offspring of women with diabetes or mild gestational hyperglycemia (MGH). Based on oral glucose tolerance test results and glycemic ...
DNA damage in peripheral blood mononuclear cells of patients undergoing anti-tuberculosis treatment
(Elsevier B.V., 2012-08-30)
Tuberculosis (TB), a chronic infectious disease, is a major cause of morbidity and mortality worldwide. Expression of iNOS and consequent production of NO during the inflammatory process is an important defense mechanism ...
DNA damage in peripheral blood mononuclear cells of patients undergoing anti-tuberculosis treatment
(Elsevier B.V., 2012-08-30)
Tuberculosis (TB), a chronic infectious disease, is a major cause of morbidity and mortality worldwide. Expression of iNOS and consequent production of NO during the inflammatory process is an important defense mechanism ...
DNA damage in wistar kyoto rats exercised during pregnancy
(2017-01-01)
Purpose: To evaluate DNA damage levels in pregnant rats undergoing a treadmill exercise program. Methods: Wistar Kyoto rats were allocated into two groups (n= 5 animals/group): non-exercise and exercise. The pregnant rats ...
Influence of endogenous and synthetic female sex hormones on human blood cells in vitro studied with comet assay
(2007-08-01)
The comet assay has been conducted with numerous cell lines to assess in vitro genotoxicity. In order to use the comet assay as part of an in vitro test for evaluating genotoxicity, however, there are cell-specific factors ...
Influence of endogenous and synthetic female sex hormones on human blood cells in vitro studied with comet assay
(2007-08-01)
The comet assay has been conducted with numerous cell lines to assess in vitro genotoxicity. In order to use the comet assay as part of an in vitro test for evaluating genotoxicity, however, there are cell-specific factors ...
Overtraining is associated with DNA damage in blood and skeletal muscle cells of Swiss mice
(2013)
Abstract: Background: The alkaline version of the single-cell gel (comet) assay is a useful method for quantifying DNA damage. Although some studies on chronic and acute effects of exercise on DNA damage measured by the ...